Explores the uses of TXRF in micro- and trace analysis, and in surface- and near-surface-layer analysis • Pinpoints new applications of TRXF in different fields of biology, biomonitoring, material and life sciences, medicine, toxicology, forensics, art history, and archaeometry • Updated and detailed sections on sample preparation taking into account nano- and picoliter techniques • Offers helpful tips on performing analyses, including sample preparations, and spectra recording and interpretation • Includes some 700 references for further study
Generally, books on mathematical statistics are restricted to the case of independent identically distributed random variables. In this book however, both this case AND the case of dependent variables, i.e. statistics for discrete and continuous time processes, are studied. This second case is very important for today’s practitioners. Mathematical Statistics and Stochastic Processes is based on decision theory and asymptotic statistics and contains up-to-date information on the relevant topics of theory of probability, estimation, confidence intervals, non-parametric statistics and robustness, second-order processes in discrete and continuous time and diffusion processes, statistics for discrete and continuous time processes, statistical prediction, and complements in probability. This book is aimed at students studying courses on probability with an emphasis on measure theory and for all practitioners who apply and use statistics and probability on a daily basis.
A breakthrough guide employing knowledge that unites cheminformatics and bioinformatics as innovation for the future Bridging the gap between cheminformatics and bioinformatics for the first time, Computational Approaches in Cheminformatics and Bioinformatics provides insight on how to blend these two sciences for progressive research benefits. It describes the development and evolution of these fields, how chemical information may be used for biological relations and vice versa, the implications of these new connections, and foreseeable developments in the future. Using algorithms and domains as workflow tools, this revolutionary text drives bioinformaticians to consider chemical structure, and similarly, encourages cheminformaticians to consider large biological systems such as protein targets and networks. Computational Approaches in Cheminformatics and Bioinformatics covers: Data sources available for modelling and prediction purposes Developments of conventional Quantitative Structure-Activity Relationships (QSAR) Computational tools for manipulating chemical and biological data Novel ways of probing the interactions between small molecules and proteins Also including insight from public (NIH), academic, and industrial sources (Novartis, Pfizer), this book offers expert knowledge to aid scientists through industry and academic study. The invaluable applications for drug discovery, cellular and molecular biology, enzymology, and metabolism make Computational Approaches in Cheminformatics and Bioinformatics the essential guidebook for evolving drug discovery research and alleviating the issue of chemical control and manipulation of various systems.
Get up to speed on the latest Group Policy tools, features, and best practices Group Policy, Fundamentals, Security, and the Managed Desktop, 3rd Edition helps you streamline Windows and Windows Server management using the latest Group Policy tools and techniques. This updated edition covers Windows 10 and Windows Server vNext, bringing you up to speed on all the newest settings, features, and best practices. Microsoft Group Policy MVP Jeremy Moskowitz teaches you the major categories of Group Policy, essential troubleshooting techniques, and how to manage your Windows desktops. This is your complete guide to the latest Group Policy features and functions for all modern Windows clients and servers, helping you manage more efficiently and effectively. Perform true desktop and server management with the Group Policy Preferences, ADMX files, and additional add-ons Use every feature of the GPMC and become a top-notch administrator Troubleshoot Group Policy using tools, enhanced logs, Resource Kit utilities, and third-party tools Manage printers, drive maps, restrict hardware, and configure Internet Explorer Deploy software to your desktops, set up roaming profiles, and configure Offline Files for all your Windows clients—and manage it all with Group Policy settings Secure your desktops and servers with AppLocker, Windows Firewall with Advanced Security, and the Security Configuration Manager This is your comprehensive resource to staying current, with expert tips, techniques, and insight.
A mixture of theory, experiments, and simulations that provide qualitative and quantitative insights into the technology The important new technology of wireless sensor and actuator networks provides radically new communication and networking paradigms with many new applications. Wireless Sensor and Actuator Networks is a timely text that presents a fault-tolerant, reliable, low-latency, and energy-aware framework for wireless sensor and actuator networks, enabling readers to fulfill the ultimate goals of the applications—such as protecting critical infrastructures, achieving timely emergency responses, and monitoring the environment. Taking a problem-oriented approach, this resource discusses a wide range of computing and communication problems and solutions that arise in rapidly emerging wireless sensor and actuator networks, striking a balance between theory and practice. Discusses backbones as subsets of sensors or actuators that suffice for performing basic data communication operations or area sensing coverage Surveys existing data communication schemes (broadcasting, routing, multicasting, anycasting, geocasting) for sensor-actuator coordination Reviews the location service techniques Addresses the problem of energy-efficient data gathering by mobile sinks/actuators Describes protocols for coordination and topology control in sensor, actuator, and robot networks Reviews existing solutions to the sensor placement problem in wireless sensor and actuator networks This book is unique in that it addresses sensor and actuator networking in a comprehensive manner—covering all the aspects and providing up-to-date information—so that industry operators and academics from various areas can learn more about current networking trends, become aware of the possible architectures, and understand the advantages and limits in future commercial, social, and educational applications. Wireless Sensor and Actuator Networks is appropriate for graduate students in computer science, electrical engineering, and telecommunications, as well as practitioners working as engineers, programmers, and technologists.
A clear and comprehensive guide to financial modeling and valuation with extensive case studies and practice exercises Corporate and Project Finance Modeling takes a clear, coherent approach to a complex and technical topic. Written by a globally-recognized financial and economic consultant, this book provides a thorough explanation of financial modeling and analysis while describing the practical application of newly-developed techniques. Theoretical discussion, case studies and step-by-step guides allow readers to master many difficult modeling problems and also explain how to build highly structured models from the ground up. The companion website includes downloadable examples, templates, and hundreds of exercises that allow readers to immediately apply the complex ideas discussed. Financial valuation is an in-depth process, involving both objective and subjective parameters. Precise modeling is critical, and thorough, accurate analysis is what bridges the gap from model to value. This book allows readers to gain a true mastery of the principles underlying financial modeling and valuation by helping them to: Develop flexible and accurate valuation analysis incorporating cash flow waterfalls, depreciation and retirements, updates for new historic periods, and dynamic presentation of scenario and sensitivity analysis; Build customized spreadsheet functions that solve circular logic arising in project and corporate valuation without cumbersome copy and paste macros; Derive accurate measures of normalized cash flow and implied valuation multiples that account for asset life, changing growth, taxes, varying returns and cost of capital; Incorporate stochastic analysis with alternative time series equations and Monte Carlo simulation without add-ins; Understand valuation effects of debt sizing, sculpting, project funding, re-financing, holding periods and credit enhancements. Corporate and Project Finance Modeling provides comprehensive guidance and extensive explanation, making it essential reading for anyone in the field.
This book highlights the applications of coupled bioluminescence assay techniques to real-world problems in drug discovery, environmental and chemical analysis, and biodefense. It separates theoretical aspects from the applied sections in a clear and readable way. Coupled Bioluminescent Assays, explains the uses of CB technologies across drug discovery to analyze toxicity, drug receptors, and enzymes. It covers applications in environmental analysis and biodefense, including cytotoxicity, fertilizer and explosives analysis, and nerve agent and pesticide detection. This is the premier reference on coupled bioluminescent assays for chemists, biochemists, and molecular biologists.
Covering cases from Addison's disease to osteoporosis and diabetic foot ulcer, and an introductory section explaining the molecular and physiological aspects of endocrinology, Endocrinology and Diabetes: Clinical Cases Uncovered has it all. Reflecting the varied nature of the specialty, the cases cover various endocrine conditions and address the clinical presentation, diagnostic workup and potential complications, while the self-assessment section, comprising 30 MCQ, 10 SAQs and 10 EMQs, will help medical students, junior doctors, and nurses practise clinical reasoning and prepare for life on the wards.
Continuing the series' tradition of providing scholarly reviews and updates of theory and research, this twenty-seventh volume surveys developments in established areas, such as stress and well-being, consumer behavior, and employee trust, as well as newer topics such as methodological issues in the development and evaluation of multiple regression models, and an examination of the psychological impact of the physical office environment. For advanced students, academics and researchers, as well as professionals, this is the most authoritative and current guide to new developments and established knowledge in the field.
In Foundation and Endowment Investing, authors Lawrence Kochard and Cathleen Rittereiser offer you a detailed look at this fascinating world and the strategies used to achieve success within it. Filled with in-depth insights and expert advice, this reliable resource profiles twelve of the most accomplished Chief Investment Officers within today’s foundation and endowment community—chronicling their experiences, investment philosophies, and the challenges they face—and shares important lessons that can be used as you go about your own investment endeavors.
Contains practical, tried-and-tested ideas and materials for planning, organizing, and carrying out project work with children aged between 5 and 13. Combines language and skills development with activities which challenge young learners and motivate them to be independent.
Ecologists are increasingly tackling difficult issues like global change, loss of biodiversity and sustainability of ecosystem services. These and related topics are enormously challenging, requiring unprecedented multidisciplinary collaboration and rapid synthesis of large amounts of diverse data into information and ultimately knowledge. New sensors, computers, data collection and storage devices and analytical and statistical methods provide a powerful tool kit to support analyses, graphics and visualizations that were unthinkable even a few years ago. New and increased emphasis on accessibility, management, processing and sharing of high-quality, well-maintained and understandable data represents a significant change in how scientists view and treat data. These issues are complex and despite their importance, are typically not addressed in database, ecological and statistical textbooks. This book addresses these issues, providing a much needed resource for those involved in designing and implementing ecological research, as well as students who are entering the environmental sciences. Chapters focus on the design of ecological studies, data management principles, scientific databases, data quality assurance, data documentation, archiving ecological data and information and processing data into information and knowledge. The book stops short of a detailed treatment of data analysis, but does provide pointers to the relevant literature in graphics, statistics and knowledge discovery. The central thesis of the book is that high quality data management systems are critical for addressing future environmental challenges. This requires a new approach to how we conduct ecological research, that views data as a resource and promotes stewardship, recycling and sharing of data. Ecological Data will be particularly useful to those ecologists and information specialists that actively design, manage and analyze environmental databases. However, it will also benefit a wider audience of scientists and students in the ecological and environmental sciences.
Lipids and essential oils have strong antimicrobial properties – they kill or inhibit the growth of microbes such as bacteria, fungi, or viruses. They are being studied for use in the prevention and treatment of infections, as potential disinfectants, and for their preservative and antimicrobial properties when formulated as pharmaceuticals, in food products, and in cosmetics. Lipids and Essential Oils as Antimicrobial Agents is a comprehensive review of the scientific knowledge in this field. International experts provide summaries on: the chemical and biological properties of lipids and essential oils use of lipids and essential oils in pharmaceuticals, cosmetics and health foods antimicrobial effects of lipids in vivo and in vitro antimicrobial lipids in milk antimicrobial lipids of the skin antibacterial lipids as sanitizers and disinfectants antibacterial, antifungal, and antiviral activities of essential oils antimicrobial lipids in milk antimicrobial lipids of the skin antibacterial lipids as sanitizers and disinfectants antibacterial, antifungal, and antiviral activities of essential oils Lipids and Essential Oils as Antimicrobial Agents is an essential guide to this important topic for researchers and advanced students in academia and research working in pharmaceutical, cosmetic and food sciences, biochemistry and natural products chemistry, microbiology; and for health care scientists and professionals working in the fields of public health and infectious diseases. It will also be of interest to anyone concerned about health issues and particularly to those who are conscious of the benefits of health food and natural products.
Although there is increasing need for modeling and simulation in the IC package design phase, most assembly processes and various reliability tests are still based on the time consuming «test and try out» method to obtain the best solution. Modeling and simulation can easily ensure virtual Design of Experiments (DoE) to achieve the optimal solution. This has greatly reduced the cost and production time, especially for new product development. Using modeling and simulation will become increasingly necessary for future advances in 3D package development. In this book, Liu and Liu allow people in the area to learn the basic and advanced modeling and simulation skills to help solve problems they encounter. Models and simulates numerous processes in manufacturing, reliability and testing for the first time Provides the skills necessary for virtual prototyping and virtual reliability qualification and testing Demonstrates concurrent engineering and co-design approaches for advanced engineering design of microelectronic products Covers packaging and assembly for typical ICs, optoelectronics, MEMS, 2D/3D SiP, and nano interconnects Appendix and color images available for download from the book's companion website Liu and Liu have optimized the book for practicing engineers, researchers, and post-graduates in microelectronic packaging and interconnection design, assembly manufacturing, electronic reliability/quality, and semiconductor materials. Product managers, application engineers, sales and marketing staff, who need to explain to customers how the assembly manufacturing, reliability and testing will impact their products, will also find this book a critical resource. Appendix and color version of selected figures can be found at www.wiley.com/go/liu/packaging
Although bioactive compounds in milk and dairy products have been extensively studied during the last few decades – especially in human and bovine milks and some dairy products – very few publications on this topic are available, especially in other dairy species’ milk and their processed dairy products. Also, little is available in the areas of bioactive and nutraceutical compounds in bovine and human milks, while books on other mammalian species are non-existent. Bioactive Components in Milk and Dairy Products extensively covers the bioactive components in milk and dairy products of many dairy species, including cows, goats, buffalo, sheep, horse, camel, and other minor species. Park has assembled a group of internationally reputed scientists in the forefront of functional milk and dairy products, food science and technology as contributors to this unique book. Coverage for each of the various dairy species includes: bioactive proteins and peptides; bioactive lipid components; oligosaccharides; growth factors; and other minor bioactive compounds, such as minerals, vitamins, hormones and nucleotides, etc. Bioactive components are discussed for manufactured dairy products, such as caseins, caseinates, and cheeses; yogurt products; koumiss and kefir; and whey products. Aimed at food scientists, food technologists, dairy manufacturers, nutritionists, nutraceutical and functional foods specialists, allergy specialists, biotechnologists, medical and health professionals, and upper level students and faculty in dairy and food sciences and nutrition, Bioactive Components in Milk and Dairy Products is an important resource for those who are seeking nutritional, health, and therapeutic values or product technology information on milk and dairy products from the dairy cow and speciesbeyond. Areas featured are: Unique coverage of bioactive compounds in milks of the dairy cow and minor species, including goat, sheep, buffalo, camel, and mare Identifies bioactive components and their analytical isolation methods in manufactured dairy products, such as caseins, caseinates, and cheeses; yogurt products; koumiss and kefir; and whey products Essential for professionals as well as biotechnology researchers specializing in functional foods, nutraceuticals, probiotics, and prebiotics Contributed chapters from a team of world-renowned expert scientists