The textbook is based on modern organic chemistry and considers the structure and chemical transformations of organic compounds, especially those that have biological importance. Special attention is given to the chemical reactions that have analogies in living systems. The book contains about 250 problems on all topics and solutions for them. This book conforms to the Federal educational program on Bioorganic Chemistry for medical schools and universities. It is meant for students who study Bioorganic Chemistry during one term. The book may also be useful for teachers and students of specialized secondary schools with instruction conducted in English and colleges, whose main interest is medicine, pharmacy, biology and agriculture.
The textbook is based on modern organic chemistry and considers the structure and chemical transformations of organic compounds, especially those that have biological importance. Special attention is given to the chemical reactions that have analogies in living systems. The book contains about 250 problems on all topics and solutions for them.This book conforms to the Federal educational program on Bioorganic Chemistry for medical schools and universities. It is meant for students who study Bioorganic Chemistry during one term. The book may also be useful for teachers and students of specialized sec ondary schools with instruction conducted in English and colleges, whose main interest is medicine, pharmacy, biology and agriculture.
Physical Inorganic Chemistry contains the fundamentals of physical inorganic chemistry, including information on reaction types, and treatments of reaction mechanisms. Additionally, the text explores complex reactions and processes in terms of energy, environment, and health. This valuable resource closely examines mechanisms, an under-discussed topic. Divided into two sections, researchers, professors, and students will find the wide range of topics, including the most cutting edge topics in chemistry, like the future of solar energy, catalysis, environmental issues, climate changes atmosphere, and human health, essential to understanding chemistry.
Heterocyclic chemistry is of prime importance as a sub-discipline of Organic Chemistry, as millions of heterocyclic compounds are known with more being synthesized regularly Introduces students to heterocyclic chemistry and synthesis with practical examples of applied methodology Emphasizes natural product and pharmaceutical applications Provides graduate students and researchers in the pharmaceutical and related sciences with a background in the field Includes problem sets with several chapters
Edited by a highly regarded scientist and with contributions from sixteen international research groups, spanning Asia and North America, Rare Earth Coordination Chemistry: Fundamentals and Applications provides the first one-stop reference resource for important accomplishments in the area of rare earth. Consisting of two parts, Fundamentals and Applications, readers are armed with the systematic basic aspects of rare earth coordination chemistry and presented with the latest developments in the applications of rare earths. The systematic introduction of basic knowledge, application technology and the latest developments in the field, makes this ideal for readers across both introductory and specialist levels.
Effective techniques for applying Dynamic Combinatorial Chemistry In a relatively short period, Dynamic Combinatorial Chemistry (DCC) has grown from proof-of-concept experiments in a few isolated labs to a broad conceptual framework with applications to an exceptional range of problems in molecular recognition, lead compound identification, catalyst design, nanotechnology, polymer science, and others. Bringing together a group of respected experts, this overview explains how chemists can apply DCC and fragment-based library methods to lead generation for drug discovery and molecular recognition in bioorganic chemistry and materials science. Chapters cover: Basic theory Approaches to binding in proteins and nucleic acids Molecular recognition Self-sorting Catalyst discovery Materials discovery Analytical chemistry challenges A comprehensive, single-source reference about DCC methods and applications including aspects of fragment-based drug discovery, this is a core reference that will spark the development of new solutions and strategies for chemists building structure libraries and designing compounds and materials.
Metal Enolates form a class of compounds that have recently received much study because of their part in the important C-C-bond forming aldol reaction. Focusing on this important class of compounds in organic synthesis, The Chemistry of Metal Enolates features contributions on all aspects of Metal Enolate chemistry from the world?s leading experts. Delivering the exceptional quality that?s expected from the Patai Series, this text is essential reading for organic chemists.
This book is a physical chemistry textbook that presents the essentials of physical chemistry as a logical sequence from its most modest beginning to contemporary research topics. Many books currently on the market focus on the problem sets with a cursory treatment of the conceptual background and theoretical material, whereas this book is concerned only with the conceptual development of the subject. Comprised of 19 chapters, the book will address ideal gas laws, real gases, the thermodynamics of simple systems, thermochemistry, entropy and the second law, the Gibbs free energy, equilibrium, statistical approaches to thermodynamics, the phase rule, chemical kinetics, liquids and solids, solution chemistry, conductivity, electrochemical cells, atomic theory, wave mechanics of simple systems, molecular orbital theory, experimental determination of molecular structure, and photochemistry and the theory of chemical kinetics.
This book comprehensively covers iodine, its chemistry, and its role in functional materials, reagents, and compounds. • Provides an up-to-date, detailed overview of iodine chemistry with discussion on elemental aspects: characteristics, properties, iodides, and halogen bonding • Acts as a useful guide for readers to learn how to synthesize complex compounds using iodine reagents or intermediates • Describes traditional and modern processing techniques, such as starch, cupper, blowing out, and ion exchange resin methods • Includes seven detailed sections devoted to the applications of iodine: Characteristics, Production, Synthesis, Biological Applications, Industrial Applications, Bioorganic Chemistry and Environmental Chemistry, and Radioisotopes • Features hot topics in the field, such as hypervalent iodine-mediated cross coupling reactions, agrochemicals, dye sensitized solar cells, and therapeutic agents
The Second Edition demonstrates how computational chemistry continues to shed new light on organic chemistry The Second Edition of author Steven Bachrach’s highly acclaimed Computational Organic Chemistry reflects the tremendous advances in computational methods since the publication of the First Edition, explaining how these advances have shaped our current understanding of organic chemistry. Readers familiar with the First Edition will discover new and revised material in all chapters, including new case studies and examples. There’s also a new chapter dedicated to computational enzymology that demonstrates how principles of quantum mechanics applied to organic reactions can be extended to biological systems. Computational Organic Chemistry covers a broad range of problems and challenges in organic chemistry where computational chemistry has played a significant role in developing new theories or where it has provided additional evidence to support experimentally derived insights. Readers do not have to be experts in quantum mechanics. The first chapter of the book introduces all of the major theoretical concepts and definitions of quantum mechanics followed by a chapter dedicated to computed spectral properties and structure identification. Next, the book covers: Fundamentals of organic chemistry Pericyclic reactions Diradicals and carbenes Organic reactions of anions Solution-phase organic chemistry Organic reaction dynamics The final chapter offers new computational approaches to understand enzymes. The book features interviews with preeminent computational chemists, underscoring the role of collaboration in developing new science. Three of these interviews are new to this edition. Readers interested in exploring individual topics in greater depth should turn to the book’s ancillary website www.comporgchem.com, which offers updates and supporting information. Plus, every cited article that is available in electronic form is listed with a link to the article.
An updated overview of the rapidly developing field of green engineering techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.
The only singular, all-encompassing textbook on state-of-the-art technical performance evaluation Fundamentals of Performance Evaluation of Computer and Telecommunication Systems uniquely presents all techniques of performance evaluation of computers systems, communication networks, and telecommunications in a balanced manner. Written by the renowned Professor Mohammad S. Obaidat and his coauthor Professor Noureddine Boudriga, it is also the only resource to treat computer and telecommunication systems as inseparable issues. The authors explain the basic concepts of performance evaluation, applications, performance evaluation metrics, workload types, benchmarking, and characterization of workload. This is followed by a review of the basics of probability theory, and then, the main techniques for performance evaluation—namely measurement, simulation, and analytic modeling—with case studies and examples. Contains the practical and applicable knowledge necessary for a successful performance evaluation in a balanced approach Reviews measurement tools, benchmark programs, design of experiments, traffic models, basics of queueing theory, and operational and mean value analysis Covers the techniques for validation and verification of simulation as well as random number generation, random variate generation, and testing with examples Features numerous examples and case studies, as well as exercises and problems for use as homework or programming assignments Fundamentals of Performance Evaluation of Computer and Telecommunication Systems is an ideal textbook for graduate students in computer science, electrical engineering, computer engineering, and information sciences, technology, and systems. It is also an excellent reference for practicing engineers and scientists.
The new, revised and updated 7th edition of March’s Advanced Organic Chemistry clearly explains the theories and examples of organic chemistry, providing the most comprehensive resource about organic chemistry available. Readers are guided on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. The first five chapters deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Chapters 6 to 9 are concerned with general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation, and finally the relationship between structure and reactivity. The last 10 chapters cover the nature and the scope of organic reactions and their mechanisms. The 7th edition proves again it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Key features of the 7th edition: Every chapter has been updated with the most recent reaction information with references to both the primary and review literature New to the 7th edition: 5,500 references since the last edition, updates / rewrites of the retained sections, and an updated index in Appendix B Contains more than 1650 reactions and 20,000 valuable references to the primary literature Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds synthesized Guides the reader on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. Reviews of the previous edition: «…a favorite general organic chemistry text and an easy-to-use one-volume reference. We are confident that this book will remain a dominant reference and that it will reside on many chemists' personal bookshelves.» –Journal of Medicinal Chemistry «Who can hope to be seriously accepted as a member of the organic chemistry community without being in possession of at least one edition of 'March'?» –Chemistry and Industry
Whether studying chemistry as part of a degree requirement or as part of a core curriculum, students will find Chemistry Essentials For Dummies to be an invaluable quick reference guide to the fundamentals of this often challenging course. Chemistry Essentials For Dummies contains content focused on key topics only, with discrete explanations of critical concepts taught in a typical two-semester high school chemistry class or a college level Chemistry I course, from bonds and reactions to acids, bases, and the mole. This guide is also a perfect reference for parents who need to review critical chemistry concepts as they help high school students with homework assignments, as well as for adult learners headed back into the classroom who just need to a refresher of the core concepts. The Essentials For Dummies Series Dummies is proud to present our new series, The Essentials For Dummies. Now students who are prepping for exams, preparing to study new material, or who just need a refresher can have a concise, easy-to-understand review guide that covers an entire course by concentrating solely on the most important concepts. From algebra and chemistry to grammar and Spanish, our expert authors focus on the skills students most need to succeed in a subject.
Solid State Chemistry and its Applications, 2nd Edition: Student Edition is an extensive update and sequel to the bestselling textbook Basic Solid State Chemistry, the classic text for undergraduate teaching in solid state chemistry worldwide. Solid state chemistry lies at the heart of many significant scientific advances from recent decades, including the discovery of high-temperature superconductors, new forms of carbon and countless other developments in the synthesis, characterisation and applications of inorganic materials. Looking forward, solid state chemistry will be crucial for the development of new functional materials in areas such as energy, catalysis and electronic materials. This revised edition of Basic Solid State Chemistry has been completely rewritten and expanded to present an up-to-date account of the essential topics and recent developments in this exciting field of inorganic chemistry. Each section commences with a gentle introduction, covering basic principles, progressing seamlessly to a more advanced level in order to present a comprehensive overview of the subject. This new Student Edition includes the following updates and new features: Expanded coverage of bonding in solids, including a new section on covalent bonding and more extensive treatment of metallic bonding. Synthetic methods are covered extensively and new topics include microwave synthesis, combinatorial synthesis, mechano-synthesis, atomic layer deposition and spray pyrolysis. Revised coverage of electrical, magnetic and optical properties, with additional material on semiconductors, giant and colossal magnetoresistance, multiferroics, LEDs, fibre optics and solar cells, lasers, graphene and quasicrystals. Extended chapters on crystal defects and characterisation techniques. Published in full colour to aid comprehension. Extensive coverage of crystal structures for important families of inorganic solids is complemented by access to CrystalMaker® visualization software, allowing readers to view and rotate over 100 crystal structures in three dimensions. Solutions to exercises and supplementary lecture material are available online. Solid State Chemistry and its Applications, 2nd Edition: Student Edition is a must-have textbook for any undergraduate or new research worker studying solid state chemistry.